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Abstract
The purpose of this study is to examine the phytochemical composition and antimicrobial activity of Alligator pepper ( Aframamum melegueta) extract in clinical isolates. The analysis was carried out using standard method. The Phytochemical analysis of the ethanoluic extracts of aframamum melegueta showed the presence in high concentration of terpenoid while glycosides and flavonoids are present in moderate concentration. Saponins, phenols, alkaloids, and tannins were slightly present. The antimicrobial activity was carried out using agar disk diffusion method. The test showed that the ethanolic extract of aframamum melegueta had high inhibition on Escherichia coli (25mm), Staphylococcus spp. (20mm), and Salmonella spp. (20mm) while moderately ,it show inhibition on pseudomonas aeruginosa (15mm), Streptococcus spp. (16mm) and Bacillus substilis (18mm), diameter zone of inhibition. This suggests that ethanolic extract of Aframum Melegueta showed good antimicrobials properties. Therefore, Aframamum Melegueta can further be investigated on, in order to explore the possibility of producing drugs that can be used in the treatment of bacterial infections. Keywords: Bacteria Infection, Anti-bacteria, Alligator pepper, treatment