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Abstract
This study investigated the difficult biology topics as perceived by secondary school students in Nkanu East Local Government Area of Enugu State. Descriptive survey research design was adopted in the study. Population for the study: 5 secondary schools in Nkanu East Local Government Area was used. The sample size for the study was 100 biology students. Purposive random sampling technique was adopted. A structured questionnaire designed by the researcher which was face and content validated by two experts in biology education and measurement and evaluation department in Enugu State University of Science and Technology were used to collect data for the analysis. The reliability of the instrument was determined using Cronbach Alpha and reliability coefficient of 0.824 was obtained. Arithmetic mean was used to analyze the data collected for the study. The findings revealed that genetics, evolution and the cell and its environment are the topics identified as difficult to learn in biology. Students also identified lack of adequate experiment, allocated time and attention, as factors responsible for the identified topics difficult to learn in Biology. Again, students agreed that regular practical work is one of the ways of improving their difficulties in learning the topics identified difficult to learn in biology. Based on the findings, the researcher recommends that government should employ qualified and experienced biology teachers for effective teaching and learning of biology in secondary schools. Keywords: Biology, Difficulty, Secondary School, Teaching, Learning.